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Rabbit Anti- TNF-α

阅读次数:992发布时间:2012/11/7 9:13:22

Catalog Number : HZ367122 Quantity size : 0.1ml (dilute with pH
7.4 0.01 M PBS or antibody diluent )
Background: Tumor necrosis factor alpha(TNF-α) (also designated cachectin),
TNF-α(also designated lymphotoxin), TALL-1(also designated BAFF, THANK, or
BLYS ),glucocorticoid-induced TNF-related ligand (GITRL), and a
proliferation-inducing ligand (APRIL) are members of the TNF cytokine family.
TNF-α and TNF-α exhibit approximately 30% sequence homology and bind to a
common receptor complex. TNF-α is produced as a membrane precursor bound
form. TNF-α is secreted as a mature 25 kDa factor.TALL-1,a potent B cell
stimulatory factor, is functionally involved in B cell proliferation. GITRL is a 20 kDa
polypeptide that is found on vascular endothelial cells and in several peripheral
tissues (small intestine,ovary,testis and kidney )where it may modulate T
lymphocyte survival. APRIL is implicated in the regulation of infections, inflammation,
autoimmune dises, and tissue homeostasis.
pecificity :
– anti- TNF-α is a rabbit polyclonal antibody u nconjugated
– specific for TNF-α of human, mo, rat, mouse, bovine, horse, dog, pig, chi
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 17kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The
lyophilized antibody is stable at room temperature for at least one month and for
greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M
PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for
use in human, therapeutic or diagnostic applications.

原创作者:上海劲马实验设备有限公司

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